Giacomo Koch

2 papers in the library · publishing 2009-2026

Papers

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Personalized non-invasive combined magnetic and electrical stimulation of the default mode network in mild AD patients (CMES-AD): a multicentric randomized sham-controlled trial protocol.

Alzheimer's Research & Therapy July 21, 2026 Sonia Bonnì, Romina Esposito, Lucia Mencarelli et al.

Patients with Alzheimer's disease (AD) exhibit early alterations in the Default Mode Network (DMN), a key brain network involved in episodic memory where the precuneus plays a central role. Precision-targeted, non-invasive brain stimulation represents a promising strategy to improve cognitive function in individuals with dementia. The DMN can be modulated through personalized non-invasive...

DOI: 10.1186/s13195-026-02145-x Full text Default mode network Alzheimer's disease Precuneus Itbs +1

Cannabis-based treatment induces polarity-reversing plasticity assessed by theta burst stimulation in humans.

Brain Stimulation October 2009 Giacomo Koch, Francesco Mori, Claudia Codecà et al.

In animal models, the cannabinoid system has been convincingly implicated in the regulation of long-lasting synaptic plasticity. Both long-term potentiation (LTP) and depression (LTD) phenomena can be induced in the human motor cortex by transcranial magnetic theta burst stimulation (TBS). Here, we explored the potential involvement of the cannabinoid system in TBS-induced synaptic plasticity...

DOI: 10.1016/j.brs.2009.03.001 Full text