Amani Mahroug

2 papers in the library · publishing 2026

Papers

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Does co-administration of cannabidiol (CBD) influence the plasma availability of delta-9-tetrahydrocannabinol (THC) and its active metabolite in humans? A systematic review and meta-analysis.

Neuroscience & Biobehavioral Reviews August 20, 2026 Lucy Chester, Heidar Sharafi, Amani Mahroug et al.

Research on the pharmacokinetic influence of cannabidiol (CBD) on delta-9-tetrahydrocannabinol (THC) has produced equivocal results. We conducted a systematic search following PRISMA guidelines (last search: 24th November 2025, PROSPERO: CRD42023480695). Included studies were acute dosing trials that administered a) a single, fixed dose of THC and b) a matched dose of THC co-administered with...

DOI: 10.1016/j.neubiorev.2026.106910 Full text Cannabidiol Tetrahydrocannabinol Meta-analysis Pharmacokinetics +1

Acute behavioural effects of low-dose cannabidiol: A randomised crossover trial in healthy volunteers.

Journal of Psychopharmacology July 15, 2026 Lucy Chester, François-Olivier Hebert, Pamela Lachance-Touchette et al.

BACKGROUND Cannabidiol (CBD) is widely consumed in low-dose products. However, evidence for its psychotropic effects at non-clinical doses is sparse and inconsistent. AIMS To characterise the acute behavioural effects of low-dose synthetic CBD in healthy volunteers. We hypothesised that 200 mg of CBD would produce a greater peak pleasant drug effect than a placebo. METHODS In a triple-blind,...

DOI: 10.1177/02698811261464527 Full text