In Vivo Detection of Nitrous Oxide in Blood and Saliva Following Recreational Use
ACS Omega March 10, 2026 Dinesh Durán Jiménez, F. Vinckenbosch, J. Busink et al.
Nitrous oxide (N2O) is commonly used as a recreational drug, and the Dutch police have reported numerous traffic incidents related to its misuse. At the same time, the in vivo pharmacokinetics of N2O remain underexplored. In light of these facts, this study aimed to detect and quantify N2O in blood and saliva after inhalation exposure of a recreational dose. Consequently, a pilot in vivo study...