Multidimensional characterization of the physiological and behavioral effects of TCB-2 in mice
bioRxiv August 6, 2026 Mizuki Yamamoto, Hiroto Inoue, Kazuko Hayashi et al. preprint
Background and Purpose Serotonergic psychedelics affect behavior and physiology, but the relationships among these effects remain poorly understood. In rodents, the head-twitch response is used as a measure of psychedelic-like activity, yet it does not capture changes in physiological state or the performance of learned behaviors. Here, we investigated the acute effects of the 5-HT2A receptor...