Reduction of Suicidality and Depressive Symptoms with Esketamine: Focus on Gender Differences
European Psychiatry June 1, 2026 V. Martiadis, F. Raffone, S. Testa et al.
Introduction Treatment-resistant depression (TRD) is a severe condition associated with high suicide risk and limited response to conventional antidepressants. Intranasal esketamine has shown rapid efficacy in reducing depressive symptoms and suicidal ideation. Objectives This observational study assessed the real-world effectiveness of esketamine in reducing suicidal ideation, self-harm...