Ibogaine as a Double-Edged Sword: Developmental Cardiotoxicity and Neurobehavioral Alterations in Zebrafish
Behavioural Brain Research August 1, 2026 Alessandra Mara de Oliveira, Flavia R. Abe, Rafael G. Dos Santos et al.
Ibogaine has attracted increasing attention as a potential treatment for substance use disorders; however, its clinical application remains limited by well-documented cardiotoxicity, and its safety during early development is poorly understood. Here, we investigated the developmental cardiotoxic and neurobehavioral effects of ibogaine using zebrafish embryos and larvae as a translational model....