Ketamine is an anesthetic drug used recreationally for its psychoactive effects. Recently, the use of ketamine has increased. Ketamine is a chiral compound with two enantiomers, S-ketamine (esketamine) and R-ketamine (arketamine). Though the S- enantiomer is more potent, pharmaceutical ketamine is most often racemic. Asymmetric synthesis or optical resolution can be performed to increase the...