Feasibility and Tolerability of Psilocybin for Phantom Limb Pain.
Journal of Pain August 1, 2026 Jon G. Dean, Ethan Hurwitz, T. Furnish et al.
Phantom limb pain (PLP) is a refractory condition defined by pain experienced in a missing limb. Psilocybin, a classical serotonergic psychedelic drug, can alleviate various treatment-resistant disorders but has scantly been investigated for chronic pain. This placebo-controlled, double-blind, randomized clinical pilot trial (NCT05224336) tested the feasibility, tolerability, and preliminary...