Explainable and Externally Validated Resting-State fMRI Machine Learning Reveals Network Mechanisms Supporting Preserved Consciousness: A Cross-Sectional Study Comparing Minimally Conscious State and Unresponsive Wakefulness Syndrome
Linghui Dong, Hui Li, Kaiyue Han et al.
Abstract Background Accurate differentiation between minimally conscious state (MCS) and unresponsive wakefulness syndrome (UWS) is a significant clinical challenge because behavioral assessments are often constrained by patients' motor impairments and fluctuating arousal. Beyond diagnostic classification, clarifying the specific brain network mechanisms that sustain residual consciousness in...