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Aldielyson Jorge Cavalcante de Brito

4 papers in the library · 15 citations · publishing 0-2026

Papers

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Dissociation and Antidepressant Response to Subcutaneous Esketamine: A Clinical Study

Journal of Psychiatric Research July 1, 2026 K S de Freitas Goncalves, Vagner Deuel O de Tavares, Fernanda Palhano-Fontes et al.

ABSTRACT: Introduction Ketamine and esketamine have reemerged as promising interventions for treatment-resistant depression (TRD), yet debate persists regarding the clinical relevance of acute dissociative experiences. This secondary exploratory analysis examined the relationship between dissociative experiences induced by subcutaneous esketamine and antidepressant response in patients with...

DOI: 10.1016/j.jpsychires.2026.07.016 (opens in new tab) Major depressive disorder Treatment-resistant depression Depersonalization Beck depression inventory +16

Ketamine-induced altered states of consciousness: a systematic review of implications for therapeutic outcomes in psychiatric practices.

European Archives of Psychiatry and Clinical Neuroscience October 28, 2024 Kaike Thiê da Costa Gonçalves, Vagner Deuel O de Tavares, Maria Luiza de Morais Barros et al. 5 citations

This systematic review aims to elucidate the nexus between ketamine's psychoactive properties and its efficacy in treating a broad spectrum of psychiatric disorders. We searched three databases and used citation tracking to include 29 studies. Predominantly, mood disorders, including bipolar disorder (BD) and major depressive disorder (MDD) (MDD + BD: + n = 25 studies), a large part of them...

DOI: 10.1007/s00406-024-01925-6 (opens in new tab) Full text (opens in new tab) Anxiety Depression Psychedelic-assisted therapy Addiction +8

Rapid and long-lasting effects of subcutaneous esketamine on suicidality: An open-label study in patients with treatment-resistant depression.

Journal of Psychiatric Research August 1, 2024 Eduardo Igor Torquato Cardoso Lopes, Patrícia Cavalcanti-Ribeiro, Fernanda Palhano-Fontes et al. 9 citations

Therapeutics for suicide management is limited, taking weeks to work. This open-label clinical trial with 18 treatment-resistant depressive patients tested subcutaneous esketamine (8 weekly sessions) for suicidality. We noted a rapid and enduring effect of subcutaneous esketamine, lasting from one week to six months post-treatment, assessed by the Beck Inventory for Suicidality (BSI). There was...

DOI: 10.1016/j.jpsychires.2024.06.020 (opens in new tab) Full text (opens in new tab) Treatment-resistant depression Mental health treatment Suicide prevention Esketamine therapy +2

Ketamine's Altered States Meta-Analysis: The Relationship Between Psychomimetic and Clinical Effects With Focus in Depression.

Journal of Clinical Psychopharmacology Vagner Deuel O de Tavares, Kaike Thiê da Costa Gonçalves, Maria Luiza de Morais Barros et al. 1 citation

In recent years, there has been a significant focus on exploring the potential therapeutic impact of altered states of consciousness on treatment outcomes for mental illness, with the goal of enhancing therapeutic strategies and patient results. This meta-analysis was designed to investigate the potential link between the psychomimetic effects of ketamine and clinical outcomes in mental health,...

DOI: 10.1097/JCP.0000000000001946 (opens in new tab) Full text (opens in new tab) Depression Ketamine therapy Mental health treatment Psychedelic medicine