Joseph Michael Cichon

General Anesthesia Occludes Ketamine's Antidepressant Response in a Rodent Model of Chronic Stress.

Psychedelic Medicine December 1, 2024 Daniel Markman, Andrzej Z Wasilczuk, Joseph Michael Cichon 2 citations

Psychedelic-induced experiences are thought to play an important role in the therapeutic actions of rapid-acting antidepressants. General anesthesia is one scenario in which patients can be rendered unconscious and masked to the psychedelic treatment, providing a simple yet effective method to examine drug-induced changes in the brain devoid of experiences. Chronically stressed adult C57/BL6...