Fatal Methaemoglobin Intoxication Following Ketamine Infusion in a Depressed MELAS Patient: A Possible Association?
Case Reports in Critical Care 2025 J. Finsterer
Methemoglobinemia is defined as an increase in methemoglobin of > 2% of hemoglobin. Ketamine is increasingly used for severe depression. To our knowledge, a patient with mitochondrial encephalopathy, lactic acidosis and stroke‐like episodes (MELAS) who died suddenly and unexpectedly 1–12 h after ketamine infusion with high postmortem methemoglobin has not yet been reported. The patient was a...