Face-to-Face and Internet-Based Mindfulness-Based Cognitive Therapy Compared With Treatment as Usual in Reducing Psychological Distress in Patients With Cancer: A Multicenter Randomized Controlled Trial.
Journal of Clinical Oncology June 28, 2018 F. Compen, E. Bisseling, M. Schellekens et al.
Mindfulness-based cognitive therapy (MBCT) and an individual internet-based version (eMBCT) both reduced psychological distress in cancer patients more than treatment as usual (TAU). In a randomized trial of 245 distressed cancer patients, those receiving MBCT or eMBCT reported significantly less distress post-intervention (Cohen's d = .45 and .71, respectively). Both interventions also reduced fear of cancer recurrence and rumination, and improved mental health-related quality of life, mindfulness skills, and positive mental health compared to TAU. Physical health-related quality of life did not improve. Post-treatment psychiatric diagnosis prevalence was lower with MBCT (33% improvement) and eMBCT (29% improvement) versus TAU (16%), but these differences were not statistically significant.