Effects of Mindfulness-Oriented Recovery Enhancement Versus Social Support on Negative Affective Interference During Inhibitory Control Among Opioid-Treated Chronic Pain Patients: A Pilot Mechanistic Study.
Annals of Behavioral Medicine January 22, 2019 E. Garland, M. A. Bryan, Sarah E. Priddy et al.
A mindfulness-based intervention, Mindfulness-Oriented Recovery Enhancement (MORE), improved the ability to inhibit responses when exposed to pain-related emotional distractors in adults with chronic pain and long-term prescription opioid use. In a controlled trial, participants in MORE showed greater reductions in errors of commission on an Emotional Go/NoGo Task with pain-related stimuli compared with a support group. More mindfulness practice and increased nonreactivity predicted better emotional response inhibition. Improvements in emotional response inhibition were linked to later reductions in pain severity at 3-month follow-up. The results provide preliminary evidence that MORE enhances inhibitory control under negative emotional interference.