Identifying neuronal correlates of dying and resuscitation in a model of reversible brain anoxia.
Progress in neurobiology February 1, 2020 Adrien E Schramm, Antoine Carton-Leclercq, Shana Diallo et al.
We developed a new rodent model of reversible brain anoxia and performed continuous electrocorticographic (ECoG) and intracellular recordings of neocortical neurons to identify in real-time the cellular and network dynamics that successively emerge throughout the dying-to-recovery process. Along with a global decrease in ECoG amplitude, deprivation of oxygen supply resulted in an early surge of...