All-night spectral and microstate EEG analysis in patients with recurrent isolated sleep paralysis
Frontiers in Neuroscience February 8, 2024 Filip Černý, Václava Piorecká, Monika Kliková et al.
Sleep in people with recurrent isolated sleep paralysis (RISP) is disturbed even outside episodes and beyond REM sleep. Spectral analysis of full-night polysomnography recordings from 17 RISP patients and 17 controls revealed significantly higher theta power in REM and NREM 2 stages in RISP patients, with a similar trend in other stages. Alpha power showed a downward trend in deep sleep. EEG microstate analysis during NREM 3 found preserved prototypical generators but abnormal temporal dynamics, including altered transitions between microstates C and D and between A and B. The findings suggest that understanding RISP requires examining processes beyond REM, and microstate dynamics may serve as functional biomarkers.