Development and effectiveness of a mindfulness-based cognitive therapy for individuals with spinal cord injury: Changes in quality of life and inflammatory biomarkers
Figshare June 4, 2026 Chan-Woo Yeom, Onyoo Kim, Jeong-A. Yu et al.
A tailored Mindfulness-Based Cognitive Therapy (MBCT) program for inpatients with spinal cord injury (SCI) did not significantly improve overall quality of life or spiritual well-being compared to treatment as usual, but it did show benefits for participants with normal-to-mild baseline depression. The MBCT group also had increased anti-inflammatory IL-10 and decreased inflammatory sTNFR2 and CRP levels, suggesting improved inflammatory profiles. The authors argue that tailored MBCT may enhance spiritual well-being and reduce inflammation in SCI patients, especially those with lower baseline depression, but caution that randomized trials are needed.