Effectiveness of mindfulness-based stress reduction in managing fatigue, anxiety, and depression among non-small cell lung cancer patients receiving surgery and adjuvant chemotherapy: A randomized controlled trial.
Medicine April 3, 2026 Xiaoqian Liu, Hui Chen, Yuna Cheng et al.
An 8-week mindfulness-based stress reduction (MBSR) program, compared with standard care, reduced fatigue, anxiety, and depression and improved self-efficacy and mindfulness awareness in non-small cell lung cancer patients undergoing surgery and adjuvant chemotherapy. Fatigue in the MBSR group peaked at week four but returned near baseline by three months, while the control group maintained elevated fatigue. Anxiety and depression scores decreased significantly by week four and continued improving. Self-efficacy and mindfulness awareness improved consistently, with significant differences at one and three months post-intervention. The findings support integrating MBSR into routine care to improve patient well-being.