Unraveling the mediating role of anxiety and depression: Cultivating mindfulness to improve quality of life in Parkinson's disease patients.
Geriatric nursing (New York, N.Y.) June 27, 2026 Lily Man Lee Chan, Edmond Pui Hang Choi, Peter M Wayne et al.
Higher mindfulness levels are associated with reduced anxiety and depression and improved health-related quality of life in people with Parkinson's disease. Anxiety and depression fully mediated the link between the observing and non-judging facets of mindfulness and quality of life, while the acting with awareness facet was partially mediated by both anxiety and depression, and the describing facet was fully mediated by depression alone. Psychologically distressed individuals had significantly lower mindfulness and poorer quality of life than non-distressed individuals. The authors propose that integrating mindfulness interventions into clinical care for neurodegenerative diseases could improve psychological well-being.