Combining mindfulness intervention and open-label placebo treatment for chronic pain: a protocol for a feasibility study.
Pilot and Feasibility Studies August 20, 2025 Chung Jung Mun, Estrella Contreras, Yushu Xiao et al.
Mindfulness-based interventions, such as mindfulness-based stress reduction (MBSR), are efficacious mind-body treatments for chronic pain, though their modest effect sizes suggest room for improvement. Notably, recent studies indicate that mindfulness meditation does not engage the endogenous opioid system, which plays an important role in analgesia. Therefore, exploring the combination of a...