Melissa Ortega

Ayahuasca-Induced Serotonin Syndrome: Risks, Mechanisms, and Clinical Considerations

Pharmaceutical Science August 1, 2025 Melissa Ortega

Ayahuasca is a traditional Amazonian brew composed primarily of Banisteriopsis caapi and Psychotria viridis, drawing increasing interest for its psychedelic effects and potential therapeutic applications. Its pharmacological action is based on the synergistic combination of β-carbolines (harmine, tetrahydroharmine, and harmaline), which act as reversible inhibitors of monoamine oxidase A...