Advances in drug addiction research using Caenorhabditis elegans: behavioral and molecular mechanisms.
Frontiers in Cell and Developmental Biology 2026 Lihua Yang, Shuang Wu, Jiale Liu et al.
Drug addiction is a complex, chronic, and relapsing neurological disorder characterized by persistent neuroadaptation and a substantial public health burden. Because of its simple nervous system, genetic tractability, short life cycle, transparent body, and quantifiable behavioral phenotypes, C. elegans (Caenorhabditis elegans) has become a useful complementary model for studying selected...