Ketamine Responsiveness of Mice Exhibiting Anorexia‐Like Behavior Correlates With Synaptic AMPA Receptor Distribution
Synapse May 1, 2026 Bridget Xu, Cassandra Carrasco, Yi‐Wen Chen et al.
ABSTRACT Anorexia nervosa is a deadly eating disorder marked by extreme food restriction, compulsive exercise, and severe weight loss. In a prior study using the activity‐based anorexia (ABA) animal model of anorexia nervosa, 30 mg/kg, but not 3 mg/kg, of ketamine reduced relapse vulnerability, measured as increased food intake, increased body weight (BW), and reduced excessive wheel running,...