Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies.
Neural Regeneration Research May 1, 2020 Giulia Costa, Maria Antonietta De Luca, Gessica Piras et al.
Synthetic psychoactive substances, including amphetamine derivatives, hallucinogens, dissociatives, and synthetic cannabinoids, can cause toxic effects in both the peripheral and central nervous systems. Preclinical and clinical studies show that these substances, besides their abuse potential, elicit varying degrees of harm. Recreational use is increasing among young and adult people, posing a serious health risk. This review summarizes recent findings on toxicity from both older and newer synthetic drugs in humans and experimental animals.