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Mirela Praisler

5 papers in the library · publishing 2019-2021

Papers

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2C-x and DOx hallucinogens: a systematic review

Annals of the "Dunarea de Jos" University of Galati. Fascicle II, Mathematics, Physics, Theoretical Mechanics November 12, 2021 Iulia-Florentina Darie, Mirela Praisler, Cătălin Negoiţă

The drug market has seen a significant global expansion in the last decades. The synthetic designer drugs belonging to the class of amphetamines and derived phenylethylamines have experienced the greatest spread in the drug market for abuse. As phenylethylamines are organic compounds that stimulate the central nervous system of humans, many are abused as recreational drugs. A large array of...

DOI: 10.35219/ann-ugal-math-phys-mec.2021.1.07 (opens in new tab) Hallucinogen Designer drug Recreational drug Stimulant +3

Choosing relevant functional groups for optimizing Artificial Neural Networks detecting NBOMe hallucinogens

Annals of the "Dunarea de Jos" University of Galati. Fascicle II, Mathematics, Physics, Theoretical Mechanics November 28, 2019 Adelina Ion, S. Gosav, Mirela Praisler

In the early 2010s, a new group of illicit psychedelic phenethylamines was reported by the law enforcement agencies, namely the NBOMe hallucinogens. The latter seem to be sold on the black market as an alternative to LSD, due to their powerful psychoactive effects. The goal of this study was to develop an optimized Artificial Neural Network (ANN) able to classify NBOMe hallucinogens based on...

Screening for NBOMe Hallucinogens based on Artificial Neural Networks and Structural Descriptors

E-Health and Bioengineering Conference November 1, 2019 Adelina Ion, S. Gosav, Mirela Praisler

Synthetic hallucinogen trafficking is a global illicit trade. It represents one of the main dangers to public health worldwide. NBOMe is a new class of synthetic hallucinogenic drugs of abuse, which is sold through illicit channels as alternative to LSD. The most representative member of the NBOMe class is 25I-NBOMe, a derivative of 2,5-dimethoxy-4-iodophenetylamine (2C-I). In this study we are...

Artificial neural network designed to identify NBOMe hallucinogens based on 3D- MoRSE descriptors and topological descriptors

International Conference on System Theory, Control and Computing October 1, 2019 Adelina Ion, S. Gosav, Mirela Praisler et al.

Trafficking of synthetic hallucinogens remains one of the most serious threats to public health and safety, both globally and nationally. A novel group of toxic phenethylamine derivatives, referred to as NBOMe, recently gained prominence on the illicit market. 25I-NBOMe is a potent synthetic derivative of 2,5-dimethoxy-4-iodophenetylamine (2C-I), which is a classical hallucinogen with...

Artificial Neural Networks designed to identify NBOMe hallucinogens based on the most sensitive molecular descriptors

International Conference on Information Science, Electronics and Electrical Engineering October 1, 2019 Adelina Ion, S. Gosav, Mirela Praisler

Drugs are largely responsible for a high percentage of the public health problems and drug-related mortality worldwide. The illicit drug market is constantly evolving in order to circumvent controls and confiscations. NBOMe is a newly discovered class of hallucinogenic drugs. Their representative synthetic derivative is 25I-NBOMe, which is sold on illicit channels in the form of powder or...