Analogues de l’ayahuasca : le chamanisme de synthèse
Annales de Toxicologie Analytique August 21, 2018 J. Langrand, L. Dufayet, A. Villa et al.
A 42-year-old man attempted to extract dimethyltryptamine (DMT) from powdered Mimosa hostilis root bark using a 10-step method found online, involving sodium hydroxide, vinegar, naphtha, ammonia, and basic lab equipment. After smoking the resulting paste, he experienced chest pain, nausea, dizziness, palpitations, tremors, and anxiety, but no hallucinogenic effects. His clinical exam showed only dysarthria, blood pressure was 144/87 mm Hg, and ECG was normal. Urine toxicology was negative, and a specific blood DMT test by LC-MS/MS (detection limit 1 ng/mL) was also negative. This was his first unsuccessful attempt; online reports describe success by more experienced operators. Mimosa hostilis root bark contains about 0.5% DMT. By inhalation, DMT does not require a monoamine oxidase inhibitor, avoiding serotonin syndrome risk.