Regulation of neural responses to emotion perception by ketamine in individuals with treatment-resistant major depressive disorder
Translational Psychiatry February 17, 2015 James W. Murrough, Katherine A. Collins, Jessica Fields et al. 111 citations
The glutamate N-methyl-D-aspartate receptor antagonist ketamine has demonstrated antidepressant effects in individuals with treatment-resistant major depressive disorder (TRD) within 24 h of a single dose. The current study utilized functional magnetic resonance imaging (fMRI) and two separate emotion perception tasks to examine the neural effects of ketamine in patients with TRD. One task used...