Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation.
October 1, 1999 R. Andrew Chambers, J. Douglas Bremner, Bita Moghaddam et al. 140 citations
Dissociative cognitive and perceptual alterations commonly occur at the time of traumatization and as an enduring feature of post-traumatic stress disorder (PTSD). After stress exposure, dissociative symptoms are a predictor of the development of PTSD. Recent preclinical data suggest that stress stimulates the cortico-limbic release of glutamate. The glutamate that is released during stress in...