Toxicity of methylenedioxymethamphetamine (MDMA) in the dog and the rat.
Fundamental and applied toxicology : official journal of the Society of Toxicology July 1, 1987 C H Frith, L W Chang, D L Lattin et al.
Methylenedioxymethamphetamine (MDMA) was administered to dogs and rats orally once a day for a 28-day period to evaluate the morphological and neuropathological effects. Major clinical signs associated with the administration of MDMA in the dog included circling, depression, dilated pupils, hyperactivity, rapid breathing, and salivation. Major clinical signs in the rat included hyperactivity,...