Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression.
Frontiers in Neuroscience 2025 Kasper Recourt, Joop van Gerven, Nadieh Drenth et al. 1 citation
Ketamine demonstrates robust and rapidly occurring antidepressant effects in patients with difficult-to-treat major depressive disorder. Ketamine's antidepressant effects and its impact on functional networks in non-resistant forms of major depressive disorder are expected to provide valuable insight into ketamine's mechanism of action related to depression. This study employs an existing...
DOI: 10.3389/fnins.2025.1531375 (opens in new tab)
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Major depressive disorder
Nmda receptor
Functional MRI
Glutamatergic modulator
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