Dream recall in cognitively healthy older adults: associations with blood p ‐tau217 levels, APOE ε4 carriage, and cognitive decline
Alzheimer s & Dementia December 1, 2025 Darren M. Lipnicki, Meritxell Valenti, Elizabeth Lucia Valeriano‐Lorenzo et al.
Abstract Background Evidence suggests that dreaming is subserved by the default mode network (DMN) (Domhoff, 2022. The Neurocognitive Theory of Dreaming ). β‐amyloid plaques and phosphorylated tau ( p ‐tau) protein tangles accumulate and contribute to abnormal functionality in the DMN long before clinical Alzheimer's disease, and similarly early abnormal DMN functionality is shown by...