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Li Huang

2 papers in the library · 18 citations · publishing 2024-2026

Papers

Comparative Analysis of Hemodynamic Effects of Remimazolam and Propofol Combined with Esketamine in Colonoscopic Procedures in the Elderly.

Drug Design, Development and Therapy January 1, 2024 Bo-Ran Deng, Yang Zhang, Zi-Feng Xie et al. 18 citations

In elderly patients undergoing painless colonoscopies, a combination of remimazolam and esketamine causes fewer drops in blood pressure and other hemodynamic complications than propofol plus esketamine. In a randomized trial with 754 patients, hypotension occurred in 9.78% of those given remimazolam-esketamine versus 23.57% in the propofol-esketamine group. The remimazolam group also had lower rates of sinus tachycardia, sinus bradycardia, and less need for blood-pressure-supporting drugs. Both sedative regimens achieved 100% sedation success, but the remimazolam combination led to a longer time to fall asleep yet faster recovery, along with less respiratory depression and injection pain. The findings indicate remimazolam with esketamine provides superior hemodynamic stability and safety for this population.

DOI: 10.2147/DDDT.S490179 (opens in new tab) Full text (opens in new tab) Esketamine Elderly patients Hemodynamic effects Remimazolam +5

A Wearable Brain-Computer Interface for Mitigating Car Sickness via Attention Shifting.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) April 1, 2026 Jiawei Zhu, Xiaoyu Bao, Qiyun Huang et al.

A wearable mindfulness brain-computer interface (BCI) that uses electroencephalography (EEG) and artificial intelligence to assess a user's focus on breathing and provide real-time audiovisual feedback can reduce car sickness symptoms. In two real-world experiments with over 100 participants susceptible to car sickness, over 83% rated the BCI-based attention shifting as effective, with significant reductions in severity, especially for those with severe symptoms. EEG data analysis identified a neurobiological signature of car sickness, offering mechanistic insight into the intervention's efficacy. The authors propose this as a nonpharmacological alternative to pharmacological treatments with adverse side effects.

DOI: 10.1002/advs.202513040 (opens in new tab) Full text (opens in new tab) Attention shifting Audiovisual neurofeedback Brain–computer interface bci Car sickness +2