Alteration of Consciousness by Anaesthetics: A Multiscale Modulation from the Molecular to the Systems Level
Journal of Consciousness Studies June 1, 2022 Marco Cavaglià, E. A. Zizzi, S. Dombrowski et al.
General anaesthesia has been used in medical practice since the mid-nineteenth century, but its pharmacological mechanism of action is still not entirely clear. In a top-down approach, investigations probe smaller and smaller scales to shed light on how anaesthetics disrupt or alter neural activity, ultimately resulting in loss of consciousness. In the past few decades, advances in neuroscience...