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Yu Peng

2 papers in the library · 2 citations · publishing 2024-2025

Papers

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Lithium attenuates ketamine-induced long-term neurotoxicity through DISC1-mediated GSK-3β/β-catenin and ERK/CREB pathways.

Toxicology Letters April 1, 2025 Ting-Ting Yang, Zi-Wen Guo, Fang Zhang et al. 2 citations

Ketamine, an antagonist of N-methyl-D-aspartate receptor, is extensively employed in pediatric anesthesia. Multiple studies have shown that repeated ketamine exposure induces neuroapoptosis, synaptic changes and cognitive deficits during neurodevelopment. Therefore, it is essential to elucidate the mechanisms of ketamine-induced neurotoxicity and develop therapies to mitigate its harmful...

DOI: 10.1016/j.toxlet.2025.02.012 (opens in new tab) Full text (opens in new tab) Disc1 Erk/creb pathway Gsk-3β/β-catenin pathway Neurotoxicity +5

Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder Symptoms, emotional exhaustion and coping styles of Emergency Nurses: A Randomized Clinical Trial

Authorea Preprints March 23, 2024 Wei Sun, Yuan Yuan, Yushu Wang et al. preprint

Background: Post-traumatic stress disorder (PTSD) is one of the most prevalent mental health issues among emergency nurses, particularly in the aftermath of the COVID-19 pandemic. However, there is a scarcity of empirical studies on improving PTSD and related symptoms. Objective: To investigate the effectiveness of the mindfulness-based stress reduction (MBSR) program in reducing PTSD symptoms,...