Astrocytic Calcium and Default Mode Network Dysfunction in Early Stage AD
Alzheimer's Disease - Diagnostics, Pathogenesis, and Treatment [Working Title] July 1, 2026 Denis Larrivee
While most theories regarding Alzheimer’s disease (AD) pathogenesis adopt a “neurocentric” perspective, increasing evidence suggests that nonneuronal cells may be a primary site of pathogenesis in early stage AD. Several years prior to the appearance of amyloid plaques and neurofibrillary tangles (NFTs), functional connectivity (FC) changes can be observed in the human cingulate cortex, a...