A randomized controlled efficacy trial of Mindfulness-Based Stress Reduction compared to an active control group and usual care for fibromyalgia: the EUDAIMON study.
Pain August 13, 2019 Adrián Pérez-aranda, A. Feliu‐Soler, J. Montero-Marín et al.
Mindfulness-Based Stress Reduction (MBSR) plus usual care reduces functional impairment in fibromyalgia more than usual care alone, both immediately after treatment (large effects) and at 12-month follow-up (medium to large effects). MBSR also outperforms a multicomponent intervention (FibroQoL) plus usual care at post-treatment (medium to large effects), but long-term advantages are modest, limited to less pain catastrophising and fibromyalginess. The number needed to treat for a 20% improvement post-treatment is 4.0 for MBSR versus usual care and 5.0 for MBSR versus FibroQoL. Improvements in functional impact are mediated by reduced psychological inflexibility and increased acting with awareness.