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A. Marsland

2 papers in the library · publishing 2017-2022

Papers

Mindfulness-Based Stress Reduction increases stimulated IL-6 production among lonely older adults: A randomized controlled trial

Brain, behavior, and immunity May 1, 2022 Emily K. Lindsay, J. D. Creswell, Harrison J. Stern et al.

Mindfulness training may boost immune responsivity in lonely older adults. In a trial of 190 adults aged 65–85, an 8-week Mindfulness-Based Stress Reduction program led to greater increases in stimulated interleukin-6 production—a marker of innate immune function—compared to a control health program. The effect was seen immediately after the intervention and persisted at a 3-month follow-up. No adverse events occurred. The findings suggest that mindfulness training could help counteract age- and stress-related declines in immunocompetence, potentially reducing infection risk and improving recovery.

Systemic Inflammation and Resting State Connectivity of the Default Mode Network

Brain, behavior, and immunity January 23, 2017 A. Marsland, Dora C. H. Kuan, L. Sheu et al.

Plasma interleukin-6 (IL-6), an indicator of systemic inflammation, is associated with specific patterns of functional connectivity within the default mode network (DMN) of the brain. In 98 adults aged 30–54, higher IL-6 levels correlated with stronger connectivity in the sub-genual anterior cingulate cortex and weaker connectivity in the dorsal medial prefrontal cortex. These findings suggest a link between immune function and brain network activity that may relate to psychological and behavioral states in health and disease.