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Pandelis Perakakis

2 papers in the library · publishing 2013-2022

Papers

The heartbeat evoked potential is a questionable biomarker in nightmare disorder: A replication study.

NeuroImage. Clinical January 1, 2022 Tamás Bogdány, Pandelis Perakakis, Róbert Bódizs et al.

Frequent nightmares are common and linked to mental health problems, but their biological basis is poorly understood. A small 2019 study reported that the heartbeat evoked potential (HEP) measured during REM sleep differed markedly between 11 nightmare sufferers and 11 controls, and correlated with depression in the nightmare group, suggesting HEP could be a biomarker. This replication attempt analyzed HEPs in two larger databases (39 and 41 participants each) using the same methods. No significant HEP differences between groups were found in either database, nor any association with depression scores. These results cast doubt on HEP as a reliable biomarker for nightmare disorder and indicate that interpreting HEP as a marker of impaired arousal and emotional processing during REM sleep is premature.

Mindfulness (Vipassana) meditation: effects on P3b event-related potential and heart rate variability.

International journal of psychophysiology : official journal of the International Organization of Psychophysiology November 1, 2013 Luis Carlos Delgado-Pastor, Pandelis Perakakis, Pailoor Subramanya et al.

Experienced Vipassana meditators showed greater P3b brain-wave amplitudes to target tones after a 30-minute meditation session compared with before meditation or after a no-meditation rest session, indicating increased attentional engagement. They also exhibited a larger increase in the LF/HF heart rate variability ratio during meditation, suggesting enhanced autonomic regulation. These findings partially support the idea that mindfulness, rooted in Vipassana, improves awareness of present experience and emotional self-regulation.