CB-1 receptor agonist drastically changes oscillatory activity, defining active sleep.
Proceedings of the National Academy of Sciences of the United States of America April 22, 2025 Irina Topchiy, Bernat Kocsis
Brain oscillations in different behavioral states are essential for cognition, and oscillopathies contribute to cognitive dysfunction in neuropsychiatric diseases. Cannabis-1 receptor (CB1-R) activation was reported to suppress theta and fast gamma activities in rats during waking exploration, and here, we show that cannabis fundamentally alters network activity during sleep as well. Prominent...