Salvinorin A Does Not Affect Seizure Threshold in Mice
Molecules March 7, 2020 Katarzyna Socała, Urszula Doboszewska, Piotr Wlaź
The κ-opioid receptor has recently gained attention as a new molecular target in the treatment of many psychiatric and neurological disorders including epilepsy. Salvinorin A is a potent plant-derived hallucinogen that acts as a highly selective κ-opioid receptor agonist. It has unique structure and pharmacological properties, but its influence on seizure susceptibility has not been studied so...