(Es)ketamine in functional neurological disorder: a systematic review
Frontiers in Psychiatry July 20, 2026 Bruce Tamilson, Michael Chitolie, Jan Coebergh et al.
Background and aimFunctional neurological disorder (FND) is a common and disabling condition for which effective treatments remain limited. Clinical outcomes are often variable, particularly in chronic and comorbid presentations. Ketamine and esketamine are increasingly used across a range of neuropsychiatric conditions. This review aimed to synthesise the existing evidence regarding their use...
DOI: 10.3389/fpsyt.2026.1872389 (opens in new tab)
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Esketamine
Functional/dissociative seizures
Conversion disorder