Isorhynchophylline is a major oxindole alkaloid found in Uncaria species which have long been used in traditional Chinese medicine. Here, we investigated the effects of isorhynchophylline and isorhynchophylline-related alkaloids on 5-hydroxytryptamine (5-HT) receptor-mediated behavioural responses in mice and 5-HT-evoked current responses in Xenopus oocytes expressing 5-HT2A or 5-HT2C...
In the context of “Kolmogorov consciousness”, the complexity of an object to be computed can be defined by the complexity of a computing system―typically a computer―represented as the number of bits in the minimal algorithm required to compute the object. In condensed matter systems under equilibrium and nonequilibrium conditions, macroscopic properties distinct from elementary ones can emerge...