Ramachandran Ramani

NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia

Proceedings of the National Academy of Sciences September 25, 2012 Alan Anticevic, Mark G. Gancsos, John D. Murray et al. 260 citations

Glutamatergic neurotransmission mediated by N-methyl-d-aspartate (NMDA) receptors is vital for the cortical computations underlying cognition and might be disrupted in severe neuropsychiatric illnesses such as schizophrenia. Studies on this topic have been limited to processes in local circuits; however, cognition involves large-scale brain systems with multiple interacting regions. A prominent...