Electrophysiological Brain Connectivity and Subjective States Evoked by Electrical Stimulation of the Human Mid-thalamus.
The Journal of neuroscience : the official journal of the Society for Neuroscience June 3, 2026 Sofia Pantis, Masaya Togo, Dian Lyu et al.
Recent developments in intracranial EEG allow direct recordings from the human thalamus, offering new insight into thalamocortical relationships in the human brain. In this study, we applied direct intracranial electrical stimulation (iES) to the mid-thalamus, within or close to the mediodorsal nucleus, to examine its impact on conscious experience and causal brain connectivity in 30 patients...