Uncompetitive antagonists of the N-methyl d-aspartate receptor (NMDAR) have demonstrated therapeutic benefit in the treatment of neurological diseases such as Parkinson's and Alzheimer's, but some also cause dissociative effects that have led to the synthesis of illicit drugs. The ability to generate NMDAR antagonists in silico is therefore desirable for both new medication development and...
Ten women subjects exhibited no evidence of waking mood change or differential dream recall as a function of their menstrual cycles. These findings indicate that, with the use of simple screening procedures, women as well as men can and should be used as subjects in research on sleep and dreams.