N-acetylcysteine modulates hallucinogenic 5-HT(2A) receptor agonist-mediated responses: behavioral, molecular, and electrophysiological studies.
Neuropharmacology June 1, 2014 Mei-Yi Lee, Chun-Cheng Chiang, Hong‐yi Chiu et al.
N-acetylcysteine (NAC) has been reported to reverse the psychotomimetic effects in the rodent phencyclidine model of psychosis and shown beneficial effects in treating patients with schizophrenia. The effect of NAC has been associated with facilitating the activity of cystine-glutamate antiporters on glial cells concomitant with the release of non-vesicular glutamate, which mainly stimulates...
DOI: 10.1016/j.neuropharm.2014.02.006 (opens in new tab)
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5-ht2a receptor
Head twitch
N-acetylcysteine
Mglur2 receptor