Neonatal phencyclidine as a model of sex-biased schizophrenia symptomatology in adolescent mice.
Psychopharmacology October 1, 2023 Ana Carolina Dutra-Tavares, Thainá P Souza, Juliana O Silva et al.
Sex-biased differences in schizophrenia are evident in several features of the disease, including symptomatology and response to pharmacological treatments. As a neurodevelopmental disorder, these differences might originate early in life and emerge later during adolescence. Considering that the disruption of the glutamatergic system during development is known to contribute to schizophrenia,...