Profiling the combination of bupropion and dextromethorphan as a treatment option for major depressive disorder.
Expert Review of Neurotherapeutics September 1, 2024 Joseph Blanco, Pamela Quimbaya, Manuel Mena et al.
Major Depressive Disorder (MDD) is a common mental health disorder marked by sadness, hopelessness, and anhedonia. Various therapies exist, but their effectiveness is limited. Dextromethorphan hydrobromide combined with bupropion hydrochloride (Auvelity®) is a recently approved alternative for treating this condition in adults. This review summarizes the neurobiology of major depression and...