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Thomas Frodl

2 papers in the library · publishing 2009-2025

Papers

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Nitrous oxide use and psychiatric disorders: a retrospective clinical cohort study on prevalence and patterns.

Frontiers in Psychiatry 2025 Rebecca Paetow, Maike Franziska Dohrn, Michelle Finner-Prével et al.

Nitrous oxide (N2O) is used for anesthetic purposes but has gained popularity as a recreational substance. Despite its potentially severe adverse effects, knowledge about N2O use within psychiatric populations is limited. This study aimed to evaluate the life-time prevalence and patterns of N2O consumption among patients with psychiatric disorders. A retrospective observational cohort study was...

Comparison of racemic ketamine and S-ketamine in treatment-resistant major depression: report of two cases.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2009 Robert Paul, Nadine Schaaff, Frank Padberg et al.

Recent studies with intravenous infusion of the NMDA receptor antagonist ketamine showed robust and rapid antidepressant effects within hours after treatment. Ketamine is a racemic mixture consisting of two enantiomers, R- and S-ketamine. In contrast to ketamine, S-ketamine is reported to be less prone to psychomimetic side effects, such as derealisation and hallucinations. In this report we...