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Joseph W Y Lee

4 papers in the library · publishing 2018-2024

Papers

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Nabilone Impairs Spatial and Verbal Working Memory in Healthy Volunteers.

Cannabis and Cannabinoid Research February 1, 2024 Faiz M Kassim, Sophie Tod, Jennifer Rodger et al.

Background: Memory impairments and psychosis-like experiences can be adverse effects of cannabis use. However, reports on the cognitive impact of cannabis use are not consistent. There are also limited studies on the psychotomimetic effects of cannabinoid compounds to reveal the association between cannabis and psychosis. Therefore, we investigated the effect of acute cannabinoid intoxication...

Multi-modal and bi-directional effects of a synthetic Δ9-Tetrahydrocannabinol (THC) analogue, Nabilone, on spatio-temporal binding windows: Evidence from the projected hand illusion.

PLoS One 2024 Mark J H Lim, Rajan Iyyalol, Joseph W Y Lee et al.

Abnormally widened spatial and temporal binding windows (SBW/TBWs; length of space/time whereby stimuli are considered part of the same percept) are observed in schizophrenia. TBW alterations have been associated with altered sense of agency (hereafter referred to as agency), and an associative relationship between embodiment (body ownership) and agency has been proposed. SBWs/TBWs are...

Relationship of critical dynamics, functional connectivity, and states of consciousness in large‐scale human brain networks

Neuroimage March 1, 2019 Heonsoo Lee, Daniel Golkowski, Denis Jordan et al.

ABSTRACT Recent modeling and empirical studies support the hypothesis that large‐scale brain networks function near a critical state. Similar functional connectivity patterns derived from resting state empirical data and brain network models at criticality provide further support. However, despite the strong implication of a relationship, there has been no principled explanation of how...

Estimating the Integrated Information Measure Phi from High-Density Electroencephalography during States of Consciousness in Humans

Frontiers in Human Neuroscience February 16, 2018 Hyoungkyu Kim, Anthony G. Hudetz, Joseph W Y Lee et al.

The integrated information theory (IIT) proposes a quantitative measure, denoted as Φ, of the amount of integrated information in a physical system, which is postulated to have an identity relationship with consciousness. IIT predicts that the value of Φ estimated from brain activities represents the level of consciousness across phylogeny and functional states. Practical limitations, such as...